EMBL Barcelona

Tissue Biology and Disease Modelling


Don Ingber

Wyss Institute @ Harvard

15 October 2018 · PRBB · Barcelona

A new EMBL unit in Barcelona
focusing on Tissue Biology and Disease Modelling



Tissues and Organs

The human body is more than the sum of its parts. Molecular and cellular biology has made dramatic progress over the last few decades, however some biological phenomena, and some scientific questions, only exist at the level of multi-cellular tissues:

  • How do populations of thousands of different cells collaborate together to create emergent structures such as organs?

  • How does information at the molecular level translate up to control phenomena at the tissue level?

  • To what extent are cancerous tumours organised like developmental tissues?

  • How do adult tissues maintain their correct geometry and function despite high cellular turn-over?

  • Can we grow healthy and diseased tissues (eg. organoids) in the laboratory, to study them better?

  • Can we learn to re-build damaged tissue, or even to design novel tissues?

Questions like these will be the focus of the research groups at EMBL Barcelona. In particular, we will build interdisciplinary teams with strong use of 3D mesoscopic imaging, and dynamical computer modelling. Three of the groups have been recruited so far (see Speakers), and four more groups will be recruited over the next 2 years.


EMBL Barcelona

EMBL Barcelona is a new unit of the European Molecular Biology Laboratory (EMBL). It is hosted within the Barcelona Biomedical Research Park (PRBB) , one of the largest infrastructures in Southern Europe dedicated to biomedical research. In this highly collaborative, interdisciplinary and international environment, EMBL researchers will benefit from a partnership with the Centre for Genomic Regulation (CRG) and opportunities for collaboration with other pioneering research institutes and hospitals, both on campus and in the region. Perched on the Barcelona seafront, and within walking distance of the city’s iconic architecture, the site is bathed in the energy of this bustling, creative metropolis.

© Ferran Mateo / PRBB